Applied Pharmaceutics in Contemporary Compounding, 4e

By Robert P. Shrewsbury  •  
•  608
Print ISBN  9781640430648
• eBook ISBN  9781640430655
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Applied Pharmaceutics in Contemporary Compounding, 4e, and its accompanying website have been carefully developed for pharmacists, pharmacy educators, pharmacy students, and pharmacy technician students.

This book is designed to convey a fundamental understanding of the practices involved in developing and preparing compounded dosage forms utilizing pharmaceutical principles.

Applied Pharmaceutics in Contemporary Compounding is well illustrated to visually reinforce the content. Many of the compounding procedures are shown in step-by-step photographs or illustrations and are available as movie clips on the accompanying website.

Examples of interior pages:



What's New in this Edition
Table of Contents
About the Author
Instructor Resources
  • Writing is direct, clearly written, and concise.
  • Illustrations visually complement examples.
  • Examples guide students through difficult concepts.
  • Adequate space is provided to answer questions.
  • Formulation Records and Worksheets ask students to work through scenarios similar to those they will see in their careers.
  • The accompanying website provides pharmaceutics laboratory exercises, compounding laboratory exercises, formulation records of compounds made in the UNC laboratory, additional instructional media, and interactive question-and-answer exercises. Visit
What's New in this Edition
  • NEW “Compounding Equipment and Techniques” sidebars emphasize the purpose of various pieces of equipment, documentation, general operating instructions, and examples.
  • Most chapters now feature a chapter-end quiz.
  • The content has been separated into four sections to facilitate understanding.
  • The following chapters are new:
    • Chapter 6 provides information on revisions to USP-NF Chapter <795>.
    • Chapter 27 provides information on revisions to USP-NF Chapter <797>.
    • Chapter 33 provides information on revisions to USP-NF Chapter <800>.
    • Chapter 37 on Inhalation Administration.
    • Chapter 40 on Pharmacogenomics (dosing individual patients based on their genetics).
  • Expanded and modified content includes the following:
    • The chapter on colloids and gels has been split into two chapters (Chapters 12 and 13).
    • The chapter on aerosols, foams, and sprays has been moved to the nonsterile block of chapters (Chapter 26).
    • The entire section on sterile compounding has been updated, expanded, and re-written in accordance with new standards set by the USP.
    • The chapter on sterile compounded preparations: techniques and processes has been split into two chapters (Chapters 31 and 32).
    • The chapter on otic and intranasal preparations has been split into two chapters (Chapters 35 and 36).
    • The chapter on radiopharmaceuticals (Chapter 38) includes information on USP-NF Chapter <825>.
    • Formulation records have been updated with new beyond-use dates.
    • References have been updated.
Table of contents
Chapter 1: What is Compounding?
Chapter 2: Regulatory Landscape
Chapter 3: Quality Assurance Program
Chapter 4: Drug Product and Preparation Stability
Chapter 5: An Order to Compound
Chapter 6: USP–NF General Chapter Pharmaceutical Compounding–Nonsterile Preparations
Chapter 7: Compounding Ingredients and Equipment
Chapter 8: Weighing and Measuring
Chapter 9: Overview of Solutions
Chapter 10: Compounded Oral and Topical Solutions
Chapter 11: Flavoring, Sweetening, and Coloring Oral Preparations
Chapter 12: Colloids
Chapter 13: Gels
Chapter 14: Suspensions
Chapter 15: Liquid Emulsions
Chapter 16: Semisolid Dosage Forms
Chapter 17: Dermatological Preparations: Ointments and Pastes
Chapter 18: Lozenges and Medication Sticks
Chapter 19: Suppositories
Chapter 20: Medicated Powder Preparations
Chapter 21: Capsules
Chapter 22: Introduction to Tablets
Chapter 23: Compounded Tablets
Chapter 24: Modified-Release Drug Delivery Systems
Chapter 25: Compounded Modified-Release Preparations
Chapter 26: Aerosols, Foams, and Sprays
Chapter 27: USP–NF General Chapter Pharmaceutical Compounding–Sterile Preparations
Chapter 28: Routes of Administration for CSPs
Chapter 29: Types of Preparations and Devices Used in CSP Compounding and Dispensing
Chapter 30: Places (Facilities) for Compounding CSPs
Chapter 31: CSPs: Compounding Techniques and Competencies
Chapter 32: CSPs: Sterility Processes and Quality Assurance
Chapter 33: USP–NF General Chapter Handling Hazardous Drugs in the Health-Care Setting
Chapter 34: Ophthalmic Preparations
Chapter 35: Otic Preparations
Chapter 36: Intranasal Preparations
Chapter 37: Inhalation Administration
Chapter 38: Radiopharmaceutical Compounding
Chapter 39: Biotechnology Preparations
Chapter 40: Pharmacogenomics and Compounding
Appendix: Excipients Used in Pharmaceutical Compounding
About the Author

Robert P. Shrewsbury received his B.S. in pharmacy from the University of Oklahoma in 1972 and his Ph.D. in pharmaceutical sciences from the University of Kentucky in 1977. He joined the University of North Carolina School of Pharmacy faculty in 1980 and is currently an associate professor in the division of pharmacy practice and experiential education. His background training is in basic and applied biopharmaceutics and pharmacokinetics, and drug interaction mechanisms. More recently, his research interests have focused on classroom and laboratory instructional methodologies utilizing web-based or technology-based formats. He has authored books in pharmacy and pharmacology and has written a number of online pharmacy courses and study guides.

Instructor Resources

Answers to quizzes within the book are provided for instructors.